April 2, 2008 Amending Agreement between PharmAthene, Inc., PharmAthene UK Limited and PharmAthene US Corporation and Avecia Investments Limited, Avecia Biologics Limited and Avecia Biologics, Inc.10.1 Master Services Agreement dated April 2, 2008 by and between PharmAthene UK Limited and Avecia Biologics Limited*99.1 April 2, 2008 press release announcing the completion of the acquisition of Avecia`s vaccine business.*Document is subject by amendment. The amendments set out in clause 2 (amendments to the amended and adapted loan agreement) of this amending agreement No 2 are effective and the amended and adapted loan agreement is amended accordingly, from the date on which the agent has received, in form and in its content, all the documents listed in clause 3 (conditions precedent) satisfactory to the agent. The terms and definitions in this Amending Agreement No 2 shall have the same meaning as in the amended and adapted loan agreement, unless otherwise provided. . Words replaced by paragraph 8 of the 1994 Agreement. . . .